Process for preparing an improved composition of the zinc salt of bacitracin for veterinary use as growth promoter

There is disclosed a stable granulated feed grade composition of the antibiotic bacitracin, which is isolated from the fermentation broth of Bacillus licheniformis by means of adding zinc ions, the broth is centrifuged and the heavy portion, containing the greater part of the antibiotic, is dried in...

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Bibliographic Details
Main Authors CIMERMAN, RADO, POKORNY, MIROSLAV, PETRAVIC, JANKO, BERNIK, JANEZ, REPSE, JOZE
Format Patent
LanguageEnglish
French
German
Published 24.06.1987
Edition4
Subjects
CHEMISTRY
FODDER
FOODS OR FOODSTUFFS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Summary:There is disclosed a stable granulated feed grade composition of the antibiotic bacitracin, which is isolated from the fermentation broth of Bacillus licheniformis by means of adding zinc ions, the broth is centrifuged and the heavy portion, containing the greater part of the antibiotic, is dried in a spray drier. To the powder obtained in such a manner, there are added CaCO3 to commercial concentration and optionally other additives, such as dextrose, starch, soya meal, lignosulfonates or hydroxypropyl methyl cellulose in various concentrations, and said blends are converted into compacted forms or pellets. These are then ground and sieved to a defined particle size. For compacting and pelleting also commercially available pulverulent compositions can be used. The obtained granulated composition is for 10 to 40 % more stable in ready-for-use fodders than the pulverulent form and, due to its non-pulverulence, it is more suitable for preparing fodder.
Bibliography:Application Number: EP19860117193