PROCESS FOR THE PREPARATION OF PTERIDINE DERIVATIVES

Pteridine derivatives of general formula (I) in which R is hydrogen or methyl, i.e. aminopterin or methotrexate, are made by the action of a silazane on a pteridine derivative of formula (II)

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Bibliographic Details
Main Author ZIMMERMANN, PIERRE
Format Patent
LanguageEnglish
French
Published 31.01.1990
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Pteridine derivatives of general formula (I) in which R is hydrogen or methyl, i.e. aminopterin or methotrexate, are made by the action of a silazane on a pteridine derivative of formula (II)
Bibliography:Application Number: EP19860402544