Use of gyrase blocking agents in decontaminating cell cultures infested by mycoplasmas

• Main Authors: ZEILER, HANS-JOACHIM, HUEBNER, GUENTER, BRUNNER, HELMUT, DR
• Format: Patent
• Language: English; French; German
• Published: 13.05.1987
• Subjects: BEER; BIOCHEMISTRY; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; ENZYMOLOGY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Die Erfindung betrifft die Verwendung von Chinolon- und 1,8-Naphthyridon-3-carbonsäuren der Formel (I) in welcher R¹, R², R A und X die in der Beschreibung angegebene Bedeutung haben, zur Dekontamination Mycoplasmen-infizierter Zellkulturen, Zubereitungen zur Dekontamination Mycoplasmen-infizierter Zellkulturen sowie Chinolon- und 1,8-Naphthyridon-3-carbonsäuren enthaltende Zellkulturmedien. Quinoline- and 1,8-naphthyridone-3-carboxylic acids of the formula (I) in which R , R , R, A and X have the meanings given in the description, are used for decontaminating mycoplasma-infected cell cultures.