ANTI-TUMOR MEDICAMENT

This disclosure describes compositions of matter useful as growth inhibitors of transplanted tumors in mammals; and discloses the use of such compositions in medicaments for inducing the prevention of, regression and/or palliation of, various types of tumors in mammals (mammary cancer, liver cancer,...

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Bibliographic Details
Main Authors TAKAHASHI, KOICHIRO, NUMASAKI, YOSO, OHATA, ISAO
Format Patent
LanguageEnglish
Published 08.02.1989
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This disclosure describes compositions of matter useful as growth inhibitors of transplanted tumors in mammals; and discloses the use of such compositions in medicaments for inducing the prevention of, regression and/or palliation of, various types of tumors in mammals (mammary cancer, liver cancer, skin cancer, etc.), said medicaments comprising a compound of the following formula:whereinA represents an imidazolyl group or a pyridyl group, ℓ represents 0 to 1,m and n represent the same or different,represents an integer of 1 to 6, and,R represents a hydrogen atom or a lower alkyl group or a salt thereof:The above formula compounds have low toxicity, and it is expected to apply various types of administration thereof such as oral administration and parenteral administration. In particular, it is expected that the compounds are useful as new type of medical (anti-cancer) compounds which can be administered orally.
Bibliography:Application Number: EP19860304966