IMPROVEMENTS IN AND RELATING TO OCTAHYDROTHIAZOLO(4,5-G)QUINOLINES

Trans-(±)-2,5-optionally substituted-octahydrothiazolo [4,5-g]quinolines, or their enantiomers, or their pharmaceutically-acceptable acid addition or quaternary salts thereof, are useful as dopamine agonists. They have the formulawhereinR is H, benzyl, methyl, ethyl, n-propyl or allyl;R1is H, OH, ha...

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Bibliographic Details
Main Authors KORNFELD, EDMUND CARL, TITUS, ROBERT DANIEL
Format Patent
LanguageEnglish
Published 25.09.1991
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Trans-(±)-2,5-optionally substituted-octahydrothiazolo [4,5-g]quinolines, or their enantiomers, or their pharmaceutically-acceptable acid addition or quaternary salts thereof, are useful as dopamine agonists. They have the formulawhereinR is H, benzyl, methyl, ethyl, n-propyl or allyl;R1is H, OH, halogen, methyl, HN2, NHC1-3 alkyl, N(C1-3 alkyl)2, 1-pyrrolidinyl, NHCOC1-3 alkyl, or NHC1-2 alkylphenyl; ora pharmaceutically-acceptable acid addition salt thereof.
Bibliography:Application Number: EP19850302852