NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF

New cephem compounds of the formula: wherein R is amino or a protected amino group; R is hydrogen, lower aliphatic hydrocarbon group which may be substituted with suitable substituent(s), cyclo(lower)alkyl or cyclo(lower)alkenyl; and R is a thiazolio group which may be substituted with suitable subs...

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Bibliographic Details
Main Authors SAKANE, KAZUO, TERAJI, TSUTOMU, GOTO, JIRO
Format Patent
LanguageEnglish
Published 15.04.1987
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:New cephem compounds of the formula: wherein R is amino or a protected amino group; R is hydrogen, lower aliphatic hydrocarbon group which may be substituted with suitable substituent(s), cyclo(lower)alkyl or cyclo(lower)alkenyl; and R is a thiazolio group which may be substituted with suitable substituent(s) or a pyridinio group substituted with substituent(s) selected from the group consisting of halogen, cyano, hydroxy, amino, acylamino, lower alkanoyl, hydroxycarbamoyl, alkylcarbamoyl, carboxy, protected carboxy, lower alkyl, hydroxy(lower)alkyl, sulfo(lower)alkyl, protected amino(lower)alkyl, amino(lower)alkyl, carboxy(lower)alkyl and hydroxyimino(lower)alkyl; and pharmaceutically acceptable salts thereof, and process for their preparation, and also a pharmaceutical composition comprising, as an effective ingredient, the above compound in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient. The invention also relates to the starting compounds. and their preparation. i
Bibliography:Application Number: EP19810104520