Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds

Novel compounds of the formula: wherein R is amino or a protected amino group, R is carboxy or a protected carboxy group, R is formyl, hydroxymethyl or acyloxymethylene, and X is -S- or -SO-, e.g. 7-[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetamido]-3-acetoxymethylen ecepham-4-carboxylic acid (syn i...

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Bibliographic Details
Main Authors TAKAYA, TAKAO, MASUGI, TAKASHI, CHIBA, TOSHIYUKI
Format Patent
LanguageEnglish
French
German
Published 14.05.1980
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel compounds of the formula: wherein R is amino or a protected amino group, R is carboxy or a protected carboxy group, R is formyl, hydroxymethyl or acyloxymethylene, and X is -S- or -SO-, e.g. 7-[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetamido]-3-acetoxymethylen ecepham-4-carboxylic acid (syn isomer), salts thereof and processes for their preparation. The invention also relates to pharmaceutical compositions comprising, as effective ingredients, the above coumpounds in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient, and to a process for their preparation. Also a process for preparing known cephem compounds of the formula starting from some of the above new compounds is described. o
Bibliography:Application Number: EP19790103946