Method for producing (3-oxo-2.3-dihydro-1h-isoindol-1h-isoindol-1-yl)acetylguanidine derivatives

The invention relates to methods for producing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives of formula (I) using 3-hydroxy-2,3-dihydro-1 H-isoindol-1-one derivatives or 3-(2-carbamoyl-phenyl) acrylic acid ester derivatives as intermediate stages, to a method for the resolution of...

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Main Authors HANNA REDA, SCHUBERT GERRIT, KEIL JOHANNES, WU XIAO-DONG, GOURAUD YVES, KLEEMANN HEINZ-WERNER, RIEKE-ZAPP JOERG, HUANG BAO-GUO
Format Patent
LanguageEnglish
Published 22.01.2012
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Summary:The invention relates to methods for producing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives of formula (I) using 3-hydroxy-2,3-dihydro-1 H-isoindol-1-one derivatives or 3-(2-carbamoyl-phenyl) acrylic acid ester derivatives as intermediate stages, to a method for the resolution of racemates and to intermediate products of the inventive method.
Bibliography:Application Number: EG2006NA00508