3H-IMIDAZO[4,5-C]PIRIDINA-6-CARBOXAMIDAS EN CALIDAD DE AGENTES ANTIINFLAMATORIOS

• Main Authors: KLINDER, KLAUS, ROENN, ROBERT, KUELZER, RAIMUND, LUBRIKS, DIMITRIJS, PRIEPKE, HENNING, SUNA, EDGARS, PELCMAN, BENJAMIN, ARNDT, KIRSTEN, DOODS, HENRI, STENKAMP, DIRK, PFAU, ROLAND, MACK, JUERGEN
• Format: Patent
• Language: Spanish
• Published: 31.10.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

La presente invención se refiere a compuestos de fórmula general Ien la que A, L, M, Q2, Q3, Q4, R1, R5, Ra, Rb, Rc, W, X, Y, Z1, Z2, Z3 se definen en la descripción, sus sales, particularmente sus sales fisiológicamente aceptables. Los compuestos tienen utilidad potencial en el tratamiento y/o la prevención de enfermedades inflamatorias y afecciones asociadas, en particular, en el tratamiento y/o la prevención del dolor. La invención también se refiere al uso de dichos compuestos como medicamentos, a composiciones farmacéuticas que los contienen y a su preparación. The present invention relates to compounds of general formula I in which A, L, M, Q2, Q3, Q4, R1, R5, Ra, Rb, Rc, W, X, Y, Z1, Z2, Z3 are defined in the description, the salts thereof, particularly the physiologically acceptable salts thereof. The compounds are of potential utility in the treatment and/or prevention of inflammatory diseases and associated conditions, in particular, in the treatment and/or prevention of pain. The invention also relates to the use of such compounds as medicaments, to pharmaceutical compositions containing them, and to their preparation.