INDUSTRIAL PROCESS FOR THE SYNTHESIS OF NOMEGESTROL-ACETATE
The invention relates to the last step of a synthetic process, in which nomegestrol-acetate of formula (I) is synthesized from 17-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution. Настоящее изобретение относит...
Saved in:
| Main Authors | , , , , , , |
|---|---|
| Format | Patent |
| Language | English Russian |
| Published |
26.05.2021
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The invention relates to the last step of a synthetic process, in which nomegestrol-acetate of formula (I) is synthesized from 17-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution.
Настоящее изобретение относится к последней стадии способа синтеза, в котором номегэстрола ацетат формулы (I) синтезируют из 17-ацетокси-6-метилен-19-норпрегн-4-ен-3,20-диона формулы (II) в присутствии Pd/C катализатора и уксусной кислоты в горячем этаноловом растворе. |
|---|---|
| AbstractList | The invention relates to the last step of a synthetic process, in which nomegestrol-acetate of formula (I) is synthesized from 17-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution.
Настоящее изобретение относится к последней стадии способа синтеза, в котором номегэстрола ацетат формулы (I) синтезируют из 17-ацетокси-6-метилен-19-норпрегн-4-ен-3,20-диона формулы (II) в присутствии Pd/C катализатора и уксусной кислоты в горячем этаноловом растворе. |
| Author | SANTA, Csaba CSOERGEI, Janos VINCZE, Peter HORVATH, Janos MAHO, Sandor BALOGH, Laszlo BENI, Zoltan |
| Author_xml | – fullname: MAHO, Sandor – fullname: SANTA, Csaba – fullname: BENI, Zoltan – fullname: CSOERGEI, Janos – fullname: VINCZE, Peter – fullname: HORVATH, Janos – fullname: BALOGH, Laszlo |
| BookMark | eNrjYmDJy89L5WSw9vRzCQ0OCfJ09FEICPJ3dg0OVnDzD1II8XBVCI70A1LBnsEK_m4Kfv6-ru6uQJX-PrqOzq4hjiGuPAysaYk5xam8UJqbQd7NNcTZQze1ID8-tbggMTk1L7Uk3tXRwNjcwsTIydCYsAoAZoUqcg |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | ПРОМЫШЛЕННЫЙ СПОСОБ СИНТЕЗА НОМЕГЭСТРОЛА АЦЕТАТА |
| ExternalDocumentID | EA037842B1 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_EA037842B13 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 13:16:34 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English Russian |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_EA037842B13 |
| Notes | Application Number: EA20190091396 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210526&DB=EPODOC&CC=EA&NR=037842B1 |
| ParticipantIDs | epo_espacenet_EA037842B1 |
| PublicationCentury | 2000 |
| PublicationDate | 20210526 |
| PublicationDateYYYYMMDD | 2021-05-26 |
| PublicationDate_xml | – month: 05 year: 2021 text: 20210526 day: 26 |
| PublicationDecade | 2020 |
| PublicationYear | 2021 |
| RelatedCompanies | RICHTER GEDEON NYRT |
| RelatedCompanies_xml | – name: RICHTER GEDEON NYRT |
| Score | 3.3311653 |
| Snippet | The invention relates to the last step of a synthetic process, in which nomegestrol-acetate of formula (I) is synthesized from... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS |
| Title | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF NOMEGESTROL-ACETATE |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210526&DB=EPODOC&locale=&CC=EA&NR=037842B1 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3dS8MwED_GFPVNpzK_8yB9K_YjbSpSpEtTN1nbsVWZT2NdM_RlG1uH_77X0qove0pIwpEc3F0ul98dwL1mzbQ5neqqNWeZSqWWqalBmWqZKZoj20EjWwCcw8juvtHXsTVuwGeNhSnzhH6XyRFRomYo73mpr1d_j1h--bdy85B-4dDyOUhcX6m8Y_RfLMNW_I4rBrEfc4VzV3hKNHQ1kznU6KCftIeXaFbIgnjvFJiU1X-DEhzD_gBpLfITaKy3LTjkdd21FhyEVbgbu5XkbU7hqRf5RYHjntcng2HMkW8EHTiSdAUZfUTYjHojEgckikPxInBl3Fc9LhIvEWdwF4iEd1XcxeT3wBPh1ds1z6G5WC5kGwh7LJHrTNdNh9J0nhomkxJVlSM1RxrZBbR3UbncPXUFRwXbini4YV9DM19v5Q2a2Ty9LTn0A5X1e3E |
| link.rule.ids | 230,309,783,888,25576,76876 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3dT8IwEL8QNOKbogY_6YPZ2-LYunXGLGZ0nZvug8A0-EQclOgLEBjx3_e2gPrCU5u2ubSX3F2v198dwK1mjrUp_eio5pRNVCq1iZrrlKmmkaM5smw0siXAOU6s4JU-D81hDT63WJgqT-h3lRwRJWqM8l5U-nrx94jlVX8rV3f5Fw7NH_3M8ZSNd4z-i6lbitd1RC_1Uq5w7ghXSfqOZjCb6l30k_bwgs1KWRBv3RKTsvhvUPwj2O8hrVlxDLXlugkNvq271oSDeBPuxu5G8lYn8BAmXlngOHQj0uunHPlG0IEjWSDI4D3BZhAOSOqTJI3Fk8CVaaS6XGRuJk6h7YuMByruYvR74JFwt9s1zqA-m89kCwi7r5DrrNMxbErzaa4bTEpUVbbUbKlPzqG1i8rF7qk2NIIsjkZRmLxcwmHJwjI2rltXUC-Wa3mNJrfIbypu_QCLQ35k |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=INDUSTRIAL+PROCESS+FOR+THE+SYNTHESIS+OF+NOMEGESTROL-ACETATE&rft.inventor=MAHO%2C+Sandor&rft.inventor=SANTA%2C+Csaba&rft.inventor=BENI%2C+Zoltan&rft.inventor=CSOERGEI%2C+Janos&rft.inventor=VINCZE%2C+Peter&rft.inventor=HORVATH%2C+Janos&rft.inventor=BALOGH%2C+Laszlo&rft.date=2021-05-26&rft.externalDBID=B1&rft.externalDocID=EA037842B1 |