INDUSTRIAL PROCESS FOR THE SYNTHESIS OF NOMEGESTROL-ACETATE

The invention relates to the last step of a synthetic process, in which nomegestrol-acetate of formula (I) is synthesized from 17-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution. Настоящее изобретение относит...

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Bibliographic Details
Main Authors MAHO, Sandor, SANTA, Csaba, BENI, Zoltan, CSOERGEI, Janos, VINCZE, Peter, HORVATH, Janos, BALOGH, Laszlo
Format Patent
LanguageEnglish
Russian
Published 26.05.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:The invention relates to the last step of a synthetic process, in which nomegestrol-acetate of formula (I) is synthesized from 17-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution. Настоящее изобретение относится к последней стадии способа синтеза, в котором номегэстрола ацетат формулы (I) синтезируют из 17-ацетокси-6-метилен-19-норпрегн-4-ен-3,20-диона формулы (II) в присутствии Pd/C катализатора и уксусной кислоты в горячем этаноловом растворе.
Bibliography:Application Number: EA20190091396