METHOD OF PREPARING Btk INHIBITOR

• Main Authors: RAAIJMAKERS, Hans C., A, JANS, Christiaan Gerardus, Johannes, Maria, OUBRIE, Arthur A, STERRENBURG, Jan-Gerard, WIJKMANS, Jacobus C., H., M, DE MAN, Adrianus Petrus, Antonius, REWINKEL, Johannes Bernardus, Maria, BARF, Tjeerd A
• Format: Patent
• Language: English; Russian
• Published: 26.04.2021
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to a method of preparing a Btk inhibitor of formula (I) or a pharmaceutically acceptable salt thereof comprising reacting a compound (2) with 2-butynoic acid to prepare a compound (1). Изобретение относится к способу получения Btk-ингибитора формулы (1) или его фармацевтически...