METHOD OF PREPARING Btk INHIBITOR

The invention relates to a method of preparing a Btk inhibitor of formula (I) or a pharmaceutically acceptable salt thereof comprising reacting a compound (2) with 2-butynoic acid to prepare a compound (1). Изобретение относится к способу получения Btk-ингибитора формулы (1) или его фармацевтически...

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Main Authors RAAIJMAKERS, Hans C., A, JANS, Christiaan Gerardus, Johannes, Maria, OUBRIE, Arthur A, STERRENBURG, Jan-Gerard, WIJKMANS, Jacobus C., H., M, DE MAN, Adrianus Petrus, Antonius, REWINKEL, Johannes Bernardus, Maria, BARF, Tjeerd A
Format Patent
LanguageEnglish
Russian
Published 26.04.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a method of preparing a Btk inhibitor of formula (I) or a pharmaceutically acceptable salt thereof comprising reacting a compound (2) with 2-butynoic acid to prepare a compound (1). Изобретение относится к способу получения Btk-ингибитора формулы (1) или его фармацевтически приемлемой соли, включающему взаимодействие соединения (2) с 2-бутиновой кислотой для получения соединения (1)
Bibliography:Application Number: EA20190092270