USE OF LOW-DIMENSIONAL STRUCTURES AND/OR THEIR AGGLOMERATES FORMED FROM METAL OXYHYDROXIDES OR THEIR COMPOSITES AS AN AGENT TO INHIBIT TUMOR CELL PROLIFERATION

• Main Authors: BAKINA, Olga Vladimirovna, VASILJEVA, Olga, LERNER, Marat Izrailievich, MIKHAYLOV, Georgy Andreevich, PSAKHIE, Sergey Grigorievich, TURK, Boris, GLAZKOVA, Elena Alekseevna
• Format: Patent
• Language: English; Russian
• Published: 29.06.2020
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT THEREOF; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS; NANOTECHNOLOGY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; THEIR RELEVANT APPARATUS; TRANSPORTING

The object of the present invention is the use of low-dimensional structures and/or their agglomerates formed from metal oxyhydroxides or their composites comprising at least two oxyhydroxides of metals selected from the group consisting of Al, Fe, Mg and Ti, which have folds and faces of irregular shape and exhibit a local strength of an electric field generated by surface charges on the said folds, faces and edges which is no less than 10V/m, as an agent to inhibit tumor cell proliferation.. Предметом настоящего изобретения является применение низкоразмерных структур и/или их агломератов, сформированных из оксигидроксидов металлов или их композитов, состоящих по меньшей мере из двух оксигидроксидов металлов, выбранных из группы металлов, состоящей из Al, Fe, Mg и Ti, которые имеют складки и грани неправильной формы, и обладающих локальным уровнем напряженности электрического поля, формируемого поверхностными зарядами на упомянутых складках, гранях и ребрах граней, который составляет не менее 10В/м, в качестве средства для угнетения пролиферативной активности опухолевых клеток.