METHODS AND COMPOSITIONS FOR REDUCING IMMUNOSUPRESSION BY TUMOR CELLS

The present invention provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or chimeric antigen receptors (CAR)), and methods of use thereof. Изобретение отчасти относится к способам обнаружения миш...

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Bibliographic Details
Main Authors SHAFFER, Donald, WUCHERPFENNIG, Kai W, ALVAREZ ARIAS, Diana, CANTOR, Harvey I, HACOHEN, Nir, DRANOFF, Glenn, ZHOU, Penghui
Format Patent
LanguageEnglish
Russian
Published 23.06.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The present invention provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or chimeric antigen receptors (CAR)), and methods of use thereof. Изобретение отчасти относится к способам обнаружения мишеней для иммунотерапии in vivo, к терапевтическим композициям (например, мшРНК, иммунореактивные клетки, экспрессирующие мшРНК и/или химерные рецепторы антигенов (CAR)) и к способам их применения.
Bibliography:Application Number: EA20150092269