HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE

• Main Authors: ELBAN Mark, HILFIKER Mark, A, WASHBURN David, G, KALLANDER Lara, S, MANNS Sharada, EIDAM Hilary, Schenck, HOANG Tram, H, DOWDELL Sarah, E, FOX Ryan, Michael, HAMMOND Marlys, LAWHORN Brian, Griffin, PHILP Joanne, YE Guosen
• Format: Patent
• Language: English; Russian
• Published: 28.02.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Disclosed are compounds having the formulawherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including the use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity. Раскрыты соединения, имеющие формул...