HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE

Disclosed are compounds having the formulawherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including the use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity. Раскрыты соединения, имеющие формул...

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Main Authors ELBAN Mark, HILFIKER Mark, A, WASHBURN David, G, KALLANDER Lara, S, MANNS Sharada, EIDAM Hilary, Schenck, HOANG Tram, H, DOWDELL Sarah, E, FOX Ryan, Michael, HAMMOND Marlys, LAWHORN Brian, Griffin, PHILP Joanne, YE Guosen
Format Patent
LanguageEnglish
Russian
Published 28.02.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds having the formulawherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including the use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity. Раскрыты соединения, имеющие формулугде R1, R2 и R3 имеют значения, определенные в настоящем изобретении, и способы получения и применения таких соединений, включая применение в качестве ингибиторов BMP1, TLL1 и/или TLL2 и для лечения заболеваний, связанных с активностью BMP1, TLL1 и/или TLL2.
Bibliography:Application Number: EA20160091412