PROCESS FOR PREPARATION OF PYRIDO-PYRIMIDIN mTOR KINASE INHIBITORS AND SALT FORMS THEREOF

There is provided a process for the preparation of a compound of Formula 1the use of said process in the preparation of a compound of Formula 5or a phosphate, suolphate, hydrogensulphate, malate, citrate, tartrate or fumarate salt thereof, and the use of the fumarate salt in a composition for use in...

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Main Authors KENWORTHY MARTIN, NEAL, CHURCHILL GWYDION, HUW, BLADE HELEN, HYNES PETER, SAMUEL, POWELL LYN, CURRIE ANGELA, CHARLOTTE, DOBSON BENJAMIN, CHARLES, RAW STEVEN, ANTHONY
Format Patent
LanguageEnglish
Russian
Published 30.01.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is provided a process for the preparation of a compound of Formula 1the use of said process in the preparation of a compound of Formula 5or a phosphate, suolphate, hydrogensulphate, malate, citrate, tartrate or fumarate salt thereof, and the use of the fumarate salt in a composition for use in therapy. Обеспечиваются способ получения соединения формулы 1применение указанного способа для получения соединения формулы 5или его фосфатной, сульфатной, гидросульфатной, малатной, цитратной, тартратной или фумаратной соли и применение фумаратной соли в композиции для применения в терапии.
Bibliography:Application Number: EA20110000063