N-ACYL-AMINOSYRE-DIAMIDDERIVATER OG FREMGANGSMAADE TIL FREMSTILLING AF SAMME

This invention relates to a novel N-acyl acidic amino acid diamide derivative represented by the general formula or a salt thereof: wherein each of R1, R2, R3 and R4, which may be the same or different, represents a hydrogen atom or a substituted or unsubstituted alkyl, cycloalkyl, alkenyl or aralky...

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Main Authors HIRANO HIROSHI, KIBA YASUO, KAWABATA MIKIO, MIYAURA TATSUYA, SUZUKI YASUYUKI, HIRAI SHIRO, TAKAGAWA NOBORU, KODAMA TAKUYA
Format Patent
LanguageDanish
Published 13.12.1985
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to a novel N-acyl acidic amino acid diamide derivative represented by the general formula or a salt thereof: wherein each of R1, R2, R3 and R4, which may be the same or different, represents a hydrogen atom or a substituted or unsubstituted alkyl, cycloalkyl, alkenyl or aralkyl group, or R1 and R2 and/or R3 and R4, when taken together with the respective adjacent nitrogen atoms, form a substituted or unsubstituted heterocyclic group; R5 represents a substituted or unsubstituted cycloalkyl, acyl or heterocyclic group; A represents a bond or a substituted or unsubstituted alkylene, alkenylene or alkadienylene group; and n is 1, 2 or 3. Said compound has an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such a compound, to a process for the production thereof and to an anti-ulcer agent containing the same.
Bibliography:Application Number: DK19840005636