FREMGANGSMAADE TIL FREMSTILLING AF ET STEROID AF ANDROSTANRAEKKEN

The novel compound according to Claim 1 has a high local anti-inflammatory action, but only relatively weak systemic actions it can therefore be used for the local treatment of inflammations with a minimum risk of undesired systemic side effects. It is prepared by esterification of the corresponding...

Full description

Saved in:
Bibliographic Details
Main Authors BAIN B M D, PHILLIPPS G H, WOOLLETT E A, ENGLISH A F
Format Patent
LanguageDanish
Published 09.08.1979
Edition3
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
Online AccessGet full text

Cover

More Information
Summary:The novel compound according to Claim 1 has a high local anti-inflammatory action, but only relatively weak systemic actions it can therefore be used for the local treatment of inflammations with a minimum risk of undesired systemic side effects. It is prepared by esterification of the corresponding 17 beta -carboxylic acid or a functional derivative thereof, in particular with a chloromethyl chloride, bromide or iodide, or by acetylation of the corresponding chloromethyl 17 alpha -hydroxy-17 beta -carboxylate, or by replacement of iodine or bromine by chlorine, e.g. by means of a metal chloride, in a corresponding iodomethyl or bromomethyl ester.
Bibliography:Application Number: DK19790000501