BETA-LAKTAMFORBINDELSER OG FREMGANGSMAADE TIL FREMSTILLING DERAF

beta -Lactam compounds having the formula are described in which R is a carboxyl or esterified carboxyl group and R and R , which may be the same or different, may each represent a hydrogen atom; a substituted or unsubstituted alkyl, aralkyl or aryl group; or a cyano, formyl, nitro, carboxyl, esteri...

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Bibliographic Details
Main Authors NEWALL C E, TONGE A P
Format Patent
LanguageDanish
Published 11.04.1979
Edition3
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:beta -Lactam compounds having the formula are described in which R is a carboxyl or esterified carboxyl group and R and R , which may be the same or different, may each represent a hydrogen atom; a substituted or unsubstituted alkyl, aralkyl or aryl group; or a cyano, formyl, nitro, carboxyl, esterified carboxyl, etherified thiol or a sulphone derivative thereof, acyl, etherified hydroxyl, carbamoyl, substituted carbamoyl, sulphamoyl, substituted sulphamoyl, hydrazinocarbonyl or protected hydrazinocarbonyl group together with, in the case where R is a carboxyl group and/or R and/or R is a carboxyl group, salts thereof. Processes for preparing the compounds and pharmaceutical compositions containing them are also disclosed and intermediates of use in their preparation are described. The compounds are of use as antibiotics or as beta -lactamase inhibitors.
Bibliography:Application Number: DK19780004478