FREMGANGSMAADE TIL STRUKTURFRANSFORMATION AF RHOMBOEDRISK KRYSTALLISERET INSULIN SAMT FORHALET VIRKENDE KRYSTALSUSPENSION AF INSULIN FREMSTILLET VED FREMGANGSMAADEN
1. A process for the structural transformation of rhombohedrally crystallized insulin, preferably of pig origin, having a 4-Zn structure to rhombohedrons having a 2-Zn structure, which comprises maintaining the crystals having a 4-Zn structure in an aqueous medium containing less than 6% of sodium c...
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| Main Author | |
|---|---|
| Format | Patent |
| Language | Danish |
| Published |
23.02.1981
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| Edition | 3 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | 1. A process for the structural transformation of rhombohedrally crystallized insulin, preferably of pig origin, having a 4-Zn structure to rhombohedrons having a 2-Zn structure, which comprises maintaining the crystals having a 4-Zn structure in an aqueous medium containing less than 6% of sodium chloride, the pH of which medium is adjusted to 4.5 to 6.0 and maintained stable by addition of a buffer, at a temperature ranging from room temperature to 45 degrees C until in a sample crystals of the 4-Zn structure are no longer present. |
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| AbstractList | 1. A process for the structural transformation of rhombohedrally crystallized insulin, preferably of pig origin, having a 4-Zn structure to rhombohedrons having a 2-Zn structure, which comprises maintaining the crystals having a 4-Zn structure in an aqueous medium containing less than 6% of sodium chloride, the pH of which medium is adjusted to 4.5 to 6.0 and maintained stable by addition of a buffer, at a temperature ranging from room temperature to 45 degrees C until in a sample crystals of the 4-Zn structure are no longer present. |
| Author | THUROW H |
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| Notes | Application Number: DK19800003593 |
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| PublicationYear | 1981 |
| RelatedCompanies | HOECHST AG |
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| Snippet | 1. A process for the structural transformation of rhombohedrally crystallized insulin, preferably of pig origin, having a 4-Zn structure to rhombohedrons... |
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| SubjectTerms | CHEMISTRY COMPOUNDS OF UNKNOWN CONSTITUTION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION TRANSPORTING |
| Title | FREMGANGSMAADE TIL STRUKTURFRANSFORMATION AF RHOMBOEDRISK KRYSTALLISERET INSULIN SAMT FORHALET VIRKENDE KRYSTALSUSPENSION AF INSULIN FREMSTILLET VED FREMGANGSMAADEN |
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