EPIGENETISKE MARKØRER AF KOLOREKTALE KRÆFTFORMER OG DIAGNOSTISKE FREMGANGSMÅDER UNDER ANVENDELSE AF DET SAMME

A method of screening for the onset of a large intestine neoplasm or monitoring the progress of a neoplasm in an individual, said method comprising assessing the methylation status of a DNA region defined by Hgl9 coordinates chr6:391752..411443 and 2kb upstream of the transcription start site of IRF...

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Bibliographic Details
Main Authors Drew, horace, Duesing, Konsta Rainer, Buckley, Michael, MOLLOY, Peter Laurence, Xu, Zheng-Zhou, MITCHELL, Susan Margaret, Ross, Jason
Format Patent
LanguageDanish
Published 06.06.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:A method of screening for the onset of a large intestine neoplasm or monitoring the progress of a neoplasm in an individual, said method comprising assessing the methylation status of a DNA region defined by Hgl9 coordinates chr6:391752..411443 and 2kb upstream of the transcription start site of IRF4, in a biological sample from said individual wherein a higher level of methylation of said DNA region relative to control levels is indicative of a large intestine neoplasm or a predisposition to the onset of a large intestine neoplasm.
Bibliography:Application Number: DK20210005882T