ANGIOTENSIN-1-RECEPTORANTAGONISTER

In one aspect, this disclosure features compounds of formula (I) or a pharmaceutically acceptable salt thereof: AA1-Arg-Va1-AA4-AA5-His-Pro-AA8-OH (I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension (e.g., hypertension...

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Bibliographic Details
Main Authors STALEWSKI, Jacek, CABLE, Edward Earl
Format Patent
LanguageDanish
Published 28.06.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:In one aspect, this disclosure features compounds of formula (I) or a pharmaceutically acceptable salt thereof: AA1-Arg-Va1-AA4-AA5-His-Pro-AA8-OH (I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension (e.g., hypertension induced by pregnancy), preeclampsia, or a renal disease induced by pregnancy.
Bibliography:Application Number: DK20170727220T