Heteroaromatiske forbindelser og anvendelse deraf som dopamin-D1-ligander

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated)...

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Bibliographic Details
Main Authors MENTE, Scot Richard, LEE, Chewah, BRODNEY, Michael Aaron, EFREMOV, Ivan Viktorovich, ZHANG, Lei, GRAY, David Lawrence Firman, DOUNAY, Amy Beth, O'NEIL, Steven Victor, DAVOREN, Jennifer Elizabeth, HENDERSON, Jaclyn Louise, ROGERS, Bruce Nelsen, GREEN, Michael Eric
Format Patent
LanguageDanish
Published 12.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), age-related cognitive decline, dementia, and Parkinson's disease.
Bibliography:Application Number: DK20180000416T