DNA-forureninger i en sammensætning omfattende en parvoviral virion
The current invention relates to nucleic acid impurities in a composition comprising a parvoviral vector. In particular, the current invention shows that DNA impurities are not randomly encapsulated within a parvoviral virion. The invention therefore relates to a method for identifying and quantifyi...
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Main Authors | , |
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Format | Patent |
Language | Danish |
Published |
30.05.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The current invention relates to nucleic acid impurities in a composition comprising a parvoviral vector. In particular, the current invention shows that DNA impurities are not randomly encapsulated within a parvoviral virion. The invention therefore relates to a method for identifying and quantifying a nucleic acid impurity in a composition comprising a parvoviral vector. Finally, the current invention relates to method of determining whether a composition comprising a parvoviral vector is regarded as clinically pure. |
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Bibliography: | Application Number: DK20150801422T |