MASSIV PARALLEL KOMBINATORISK GENETIK TIL CRISPR
Described herein are methods and compositions that enable rapid generation of high-order combinations of genetic elements comprising a CRISPR guide sequence and a scaffold sequence, and a barcode for rapid identification of the combination of genetic elements encoded within a single cell or a pooled...
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Main Authors | , , |
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Format | Patent |
Language | Danish |
Published |
27.07.2020
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Subjects | |
Online Access | Get full text |
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Summary: | Described herein are methods and compositions that enable rapid generation of high-order combinations of genetic elements comprising a CRISPR guide sequence and a scaffold sequence, and a barcode for rapid identification of the combination of genetic elements encoded within a single cell or a pooled population. Also described herein compositions of inhibitors of epigenetic genes and methods for reducing cell proliferation and/or treating cancer. |
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Bibliography: | Application Number: DK20150813148T |