Partikelformede vaccineformuleringer til fremkaldelse af medfødt og adaptiv immunitet

Disclosed are compositions, kits, and methods for inducing an immune response against an infection or a disease. The compositions typically include biodegradable particles having an average effective diameter of 0.5 - 20 µm, and optionally the compositions include one or more of an adjuvant, an apop...

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Bibliographic Details
Main Authors GUPTA, Ram B, KALTENBOECK, Bernhard, OBER, Courtney, A, CHOWDHURY, Erfan U
Format Patent
LanguageDanish
Published 06.04.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed are compositions, kits, and methods for inducing an immune response against an infection or a disease. The compositions typically include biodegradable particles having an average effective diameter of 0.5 - 20 µm, and optionally the compositions include one or more of an adjuvant, an apoptosis inhibitor, and an antigen. The compositions, kits, and methods may be utilized to induce a cell-mediated response, such as a T-helper cell response, and/or a humoral response against a pathogen or a disease. In some embodiments, the compositions, kits, and methods may be utilized to induce preferentially a Th1 response versus other types of immune responses such as a Th2 response.
Bibliography:Application Number: DK20150719034T