REKOMBINANTE MIKROORGANISMER TIL FORBEDRET FREMSTILLING AF MEVALONAT, ISOPREN, ISOPRENOIDE FORLØBERE, ISOPRENOIDER OG ACETYL-COA-AFLEDTE PRODUKTER

The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, isoprenoids, and/or acetyl-CoA-derived products in recombinant microorganisms by engineering the microorganisms to comprise one or more acetylating proteins such that...

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Bibliographic Details
Main Authors MILLER, Michael, C, CERVIN, Marguerite, A, WOLFE, Alan, J, DASIKA, Madhukar, S, WELLS, Derek, H
Format Patent
LanguageDanish
Published 23.11.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, isoprenoids, and/or acetyl-CoA-derived products in recombinant microorganisms by engineering the microorganisms to comprise one or more acetylating proteins such that the expression and/or activity of the one or more acetylating proteins is modulated.
Bibliography:Application Number: DK20150708996T