Fremgangsmåde til fremstilling af peptider gennem samling af multipeptidfragmenter
Method for preparing a peptide assembly of n fragments and n-1 amino acids bearing a thiol function, represented by the formula: A1-C1-A2-C2-A3- . . . -Ci-1-Ai- . . . -Cn-1-An (I) in which A1, A2, A3, . . . Ai . . . An are peptide fragments, C1, C2, C3 . . . Ci-1 . . . Cn-1 are amino acid residues b...
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Main Authors | , , , |
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Format | Patent |
Language | Danish |
Published |
06.07.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Method for preparing a peptide assembly of n fragments and n-1 amino acids bearing a thiol function, represented by the formula: A1-C1-A2-C2-A3- . . . -Ci-1-Ai- . . . -Cn-1-An (I) in which A1, A2, A3, . . . Ai . . . An are peptide fragments, C1, C2, C3 . . . Ci-1 . . . Cn-1 are amino acid residues bearing a thiol function, n is comprised between 3 and 50, and i is 2 to n, in which a peptide-thioester is prepared of formula: A1-SR (II) in which A1 is a peptide fragment and SR is an alkyl thioester residue, R being alkyl optionally substituted, starting from a bis(2-sulphanylethyl)amino peptide. |
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Bibliography: | Application Number: DK20120705265T |