FREMGANGSMÅDE TIL FREMSTILLING AF VARIABLE IMMUNGLOBULIN-ENKELTDOMÆNER

The present disclosure relates to an improved method for the manufacture of immunoglobulin single variable domains. More specifically, the present disclosure relates to a method of producing immunoglobulin single variable domains in which the proportion of carbamylated variants is strongly reduced o...

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Bibliographic Details
Main Authors MEYVIS, Yves, SERGI, Mauro, BRIGE, Ann, WALCARIUS, Bart
Format Patent
LanguageDanish
Published 12.03.2018
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present disclosure relates to an improved method for the manufacture of immunoglobulin single variable domains. More specifically, the present disclosure relates to a method of producing immunoglobulin single variable domains in which the proportion of carbamylated variants is strongly reduced or absent and to improved immunoglobulin single variable domains obtainable by methods of the present disclosure.
Bibliography:Application Number: DK20110775994T