FREMGANGSMAADE TIL FREMSTILLING AF PYRAZINYL1,2,4-OXADIAZOLER OG KVATERNAERE SALTE DERAF

Novel substituted pyrazinyl-1,2,4-oxadiazoles of the formulas are disclosed wherein R is hydrogen or lower alkyl (C1-5), R is hydrogen or lower alkyl (C1-5), R is hydrogen or lower alkyl (C1-5), R is hydrogen or lower alkyl (C1-5), R and R can be joined to form an alkylene group of from 2-4 carbon a...

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Bibliographic Details
Main Authors CRAGOE E J, BOCK M G, SMITH R L
Format Patent
LanguageDanish
Published 20.11.1981
Edition3
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Novel substituted pyrazinyl-1,2,4-oxadiazoles of the formulas are disclosed wherein R is hydrogen or lower alkyl (C1-5), R is hydrogen or lower alkyl (C1-5), R is hydrogen or lower alkyl (C1-5), R is hydrogen or lower alkyl (C1-5), R and R can be joined to form an alkylene group of from 2-4 carbon atoms, R is lower alkyl (C1-5) X is halo, cyano or phenyl, and Y<-> is chloride, bromide or iodide, or a suitable anion. Processing for preparing the same are also described. The compounds are useful in the treatment of edema and hypertension.
Bibliography:Application Number: DK19810002146