Thiazol-pyrazolopyrimidiner som CRF1-receptorantagonister

The present invention relates to compounds of Formula (I), pharmaceutical compositions thereof, and use thereof as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric and neuroendocrine disorders, neurological diseases, and metabolic syndrome.

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Bibliographic Details
Main Authors CHEN, ZHAOGEN, HIPSKIND, PHILIP, ARTHUR, TAKAKUWA, TAKAKO, TOTH, JAMES, LEE, HEMBRE, ERIK, JAMES, MYERS, JASON, KENNETH, HAMDOUCHI, CHAFIQ, HAMDOUCHI
Format Patent
LanguageDanish
Published 06.12.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of Formula (I), pharmaceutical compositions thereof, and use thereof as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric and neuroendocrine disorders, neurological diseases, and metabolic syndrome.
Bibliography:Application Number: DK20070842582T