ANTISTOFFER MOD TGF-BETA

The present invention relates to antibody molecules, in particular antibody molecules that bindransformingrowthactor beta (TGFβ) and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFβ1, TGFβ2, and TGFβ3, so-called 'pan-specific&...

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Bibliographic Details
Main Authors HART, Celia P, JERMUTUS, Lutz U, BUCHANAN, Catriona L, Holgate, Robert G, FINCH, Donna K, DUNCAN, Alexander R, Ledbetter, Steven R
Format Patent
LanguageDanish
Published 18.03.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to antibody molecules, in particular antibody molecules that bindransformingrowthactor beta (TGFβ) and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFβ1, TGFβ2, and TGFβ3, so-called 'pan-specific' antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
Bibliography:Application Number: DK20060734583T