Farmaceutisk partikelsammensætning til udstrakt frigivelse omfattende venlafaxin

A method for the preparation of a pharmaceutical composition containing venlafaxine or a pharmaceutically acceptable salt thereof comprising the steps of (1) preparing a dispersion of venlafaxine or a venlafaxine salt in a solvent wherein venlafaxine or the venlafaxine salts has a solubility of less...

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Bibliographic Details
Main Authors PISEK, ROBERT, SEGULA, ZAKELJ, MOJCA, ZUPANCIC, SILVO
Format Patent
LanguageDanish
Published 04.02.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A method for the preparation of a pharmaceutical composition containing venlafaxine or a pharmaceutically acceptable salt thereof comprising the steps of (1) preparing a dispersion of venlafaxine or a venlafaxine salt in a solvent wherein venlafaxine or the venlafaxine salts has a solubility of less than 25 g/l at room temperature; (2) converting the dispersion of step (1) into particulate form; (3) coating the particles obtained in step (2) with a layer of a sustained release polymer, as well as pharmaceutical compositions obtainable by this process.
Bibliography:Application Number: DK20050768606T