Fremgangsmåde til fremstilling af et hydrochlorid salt af en 5-amino-7-(substitueret amino)-quinolin-3-carboxylsyre

An improved process for the preparation of 5-amino-7-(substituted-amino)-quinoline-3-carboxylic acids, having known antibacterial activity, is described wherein a 5-fluoro-7-(protected and substituted-amino)quinoline-3-carboxylic acid is converted to a 5-protected amino compound and where both prote...

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Bibliographic Details
Main Author WEMPLE, JAMES NORTON
Format Patent
LanguageDanish
Published 27.06.1994
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:An improved process for the preparation of 5-amino-7-(substituted-amino)-quinoline-3-carboxylic acids, having known antibacterial activity, is described wherein a 5-fluoro-7-(protected and substituted-amino)quinoline-3-carboxylic acid is converted to a 5-protected amino compound and where both protected amino groups are simultaneously removed to give the desired product.
Bibliography:Application Number: DK19890002397