SELEKTIVE BIOLOGISK AKTIVE 7-OXO-PROSTACYCLINDERIVATER OG FREMGANGSMAADE TIL FREMSTILLING DERAF OG FARMACEUTISKE PRAEPARATER INDEHOLDENDE DISSE

Compounds of the formula I are disclosed wherein R1 stands for hydrogen, C1-4 straight or branched alkyl or pharmacologically acceptable cation, R2 stands for hydrogen, C1-4 alkanoyl, benzoyl, or benzoyl substituted by C1-4 alkyl or halogen, and R2 can further represent tetrahydropyranyl, trialkylsi...

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Main Authors GALAMBOS, GEZA, KANAY, KAROLY, TOEMOESKOEZI, ISTVAN, DORMAN, GYOERGY, VIRAG, SANDOR, IVANICS, JOZSEF, GYOERY, PETER, STADLER, ISTVAN, KOERMOECZY, PETER, KOVACS, GABOR, KOVACS, MARIANNA
Format Patent
LanguageDanish
Published 28.06.1993
Edition5
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Summary:Compounds of the formula I are disclosed wherein R1 stands for hydrogen, C1-4 straight or branched alkyl or pharmacologically acceptable cation, R2 stands for hydrogen, C1-4 alkanoyl, benzoyl, or benzoyl substituted by C1-4 alkyl or halogen, and R2 can further represent tetrahydropyranyl, trialkylsilyl or alkoxyalkyl, A stands for ethylene, cis or trans-vinylene or -C=C-, n may represent 2, 3 or 4. The compounds are highly effective in the inhibition of thrombocyte aggregation while at the same time exert only a very small hypotensive effect.
Bibliography:Application Number: DK19850000149