CARMAMYLOXYBENZHYDROLDERIVATER, FARMACEUTISK PRAEPARAT SAMT EN FREMGANGSMAADE TIL FREMSTILLING AF DETTE

The invention relates to new carbamyloxybenzhydrol derivatives of the formula (1)whereinR1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms;R2 is hydrogen or an R3-NH-COO- group;R3 is alkyl having from one to 6 carbon atoms, cyc...

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Main Authors TOTH, EDIT, TOERLEY, JOZSEF, SZPORNY, LASZLO, GOEROEG, SANDOR, JAVOR, ANDRAS, HAJOS, GYOERGY, MADERSPACH, ANDREA, HAJDU, ISTVAN
Format Patent
LanguageDanish
Published 13.11.1989
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to new carbamyloxybenzhydrol derivatives of the formula (1)whereinR1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms;R2 is hydrogen or an R3-NH-COO- group;R3 is alkyl having from one to 6 carbon atoms, cycloalkyl having up to 7 carbon atoms, or phenyl, optionally substituted with one or more halogen(s).The compounds of the formula (I) show antilipaemic activity and can therefore be used in therapy for treating hyperlipaemia and coronary diseases. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.
Bibliography:Application Number: DK19830006015