AEROSOL INDEHOLDENDE EN PARTIKELFORMIG AKTIV FORBINDELSE
An aerosol formulation containing a particulate active substance having a mass median aerodynamic diameter (MMAD) of less than 10 µm, suspended in a nonsolvent hydrofluorocarbon fluid vehicle at a concentration of 0.2 to 5% w/v, wherein the fluid vehicle is 1,1,1,2-tetrafluoroethane (HFA 134a) or 1,...
Saved in:
Main Authors | , , |
---|---|
Format | Patent |
Language | Danish |
Published |
24.04.2017
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | An aerosol formulation containing a particulate active substance having a mass median aerodynamic diameter (MMAD) of less than 10 µm, suspended in a nonsolvent hydrofluorocarbon fluid vehicle at a concentration of 0.2 to 5% w/v, wherein the fluid vehicle is 1,1,1,2-tetrafluoroethane (HFA 134a) or 1,1,1,2,3,3,3-heptafluoropropane (HFA 227ea) and which exhibits a flocculation volume of 35% or greater 30 seconds after mixing of the active substance and vehicle. The particulate active substance may be a pharmaceutically active substance and the formulation may be for use in inhalation therapy, in particular in a metered dose inhaler. |
---|---|
Bibliography: | Application Number: DK20030722750T |