4-(aminoalkoxy)-benzofuraner som N-myristoyltransferase-inhibitorer

The present invention is directed to new bicyclic compounds of the formula [I],and pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, R5, R6, R7, Q1 Q2 and Q3 are as defined in the claims. The compounds have N-myristoyltransferase inhibitory and antifungal activity.

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Bibliographic Details
Main Authors AOKI, YUHKO, OHTSUKA, TATSUO, TSUJII, SHINJI, LIU, PINGLI, EBIIKE, HIROSATO, KAWASAKI, KENICHI, FUJII, TOSHIHIKO, MASUBUCHI, MIYAKO
Format Patent
LanguageDanish
Published 16.08.2004
Edition7
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to new bicyclic compounds of the formula [I],and pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, R5, R6, R7, Q1 Q2 and Q3 are as defined in the claims. The compounds have N-myristoyltransferase inhibitory and antifungal activity.
Bibliography:Application Number: DK19990968791T