Thalidomidanaloge forbindelser fra gruppen piperidin-2,6-dioner

Piperidin-2,6-dione derivatives of formula (I) are new. Z = (a) -C(R1)(R2)CH2- or (b) -C(R1)=CH-; R1 = phthalimide when Z = (a) or phthalimide mono- or disubstituted by OH, CH3O or NH2 when Z = (b); R2 = H or 1-6C alkyl; R3 = H, 1-6C alkyl or heteroaromatic ring; and R4 = 1-6C alkyl or (hetero)aroma...

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Bibliographic Details
Main Authors WINTER, WERNER, DR, TEUBERT, UWE, ZIMMER, OSWALD, EGER, KURT, DR, WNENDT, STEPHAN, ZWINGENBERGER, KAI
Format Patent
LanguageDanish
Published 27.12.2005
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Piperidin-2,6-dione derivatives of formula (I) are new. Z = (a) -C(R1)(R2)CH2- or (b) -C(R1)=CH-; R1 = phthalimide when Z = (a) or phthalimide mono- or disubstituted by OH, CH3O or NH2 when Z = (b); R2 = H or 1-6C alkyl; R3 = H, 1-6C alkyl or heteroaromatic ring; and R4 = 1-6C alkyl or (hetero)aromatic ring.
Bibliography:Application Number: DK19980100259T