Indol-3-carbonyl- og indol-3-sulfonyl-derivater som antagonister mod blodpladeaktiverende faktor

The present invention provides compounds of formula +TR and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, shock, respiratory distress syndrome, acute inflammation, transplanted organ reject...

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Bibliographic Details
Main Authors SHEPPARD, GEORGE, S, SUMMERS, JAMES, B, DAVIDSON, STEVEN, K, CARRERA, GEORGE, M., JR
Format Patent
LanguageDanish
Published 21.01.2002
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds of formula +TR and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
Bibliography:Application Number: DK19960911396T