Overflademodificerede NSAID-nanopartikler

Dispersible particles consisting essentially of a crystalline NSAID having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm. Pharmaceutical compositions containing the particles exhibit reduced gastric...

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Bibliographic Details
Main Authors CONZENTINO, PHILIP, SARPOTDAR, PRAMOD, P, LIVERSIDGE, GARY, G, CUNDY, KENNETH
Format Patent
LanguageDanish
Published 22.09.1997
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT THEREOF
MEDICAL OR VETERINARY SCIENCE
NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS
NANOTECHNOLOGY
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TRANSPORTING
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Summary:Dispersible particles consisting essentially of a crystalline NSAID having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm. Pharmaceutical compositions containing the particles exhibit reduced gastric irritation following oral administration and/or hastened onset of action.
Bibliography:Application Number: DK19930914224T