Phosphinyloxypropanaminium-indre saltderivater

The invention concerns the compounds of formula (I) where the substituents have various meanings, in free acid form or in salt, physiologically hydrolysable ester or pro-drug form. They can be prepared by various procedures, e.g. coupling accompanied by oxidation or thiolation and hydrolysis or thio...

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Main Authors BEBERNITZ, GREGORY R, PRASHAD, MAHAVIR, SMITH, HOWARD C, ANDERSON, ROBERT CHARLES, WILLHAUER, EDWIN B, HUGHES, JEFFREY W, FRASER, JAMES D, KAPA, PRASAD K
Format Patent
LanguageDanish
Published 26.01.1998
Edition6
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Summary:The invention concerns the compounds of formula (I) where the substituents have various meanings, in free acid form or in salt, physiologically hydrolysable ester or pro-drug form. They can be prepared by various procedures, e.g. coupling accompanied by oxidation or thiolation and hydrolysis or thiolysis, or by reduction to amino of a nitro substituent on an aromatic ring. They possess hypoglycemic activity and are thus indicated for use in the treatment of diabetes.
Bibliography:Application Number: DK19930810406T