Polyhydroxycyklopentanderivater, deres fremstilling og deres terapeutiske anvendelse

5-Amino-1-(hydroxymethyl)cyclopentane-1,2,3,4-tetraol and 2-amino-4-(hydroxymethyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]oxazole- 4,5,6-triol, which have the ability to inhibit the activity of sugar hydrolases, especially beta -glucosidase and sucrase, and which can thus be used for the treatment and...

Full description

Saved in:
Bibliographic Details
Main Authors HIDEYUKI, HARUYAMA, KIYOSHI, HAMANO, TAKESHI, KINOSHITA, RYUZO, ENIKITA, YASUYUKI, TAKAMATSU, OSAMU, ANDO, SHUJI, TAKAHASHI, MUTSUO, NAKAJIMA, AKIRA, SATO
Format Patent
LanguageDanish
Published 21.08.1995
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:5-Amino-1-(hydroxymethyl)cyclopentane-1,2,3,4-tetraol and 2-amino-4-(hydroxymethyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]oxazole- 4,5,6-triol, which have the ability to inhibit the activity of sugar hydrolases, especially beta -glucosidase and sucrase, and which can thus be used for the treatment and prophylaxis of tumorous conditions, AIDS, diabetes and obesity, can be prepared by hydrolysis of trehazolin. 2-Amino-4-(hydroxymethyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]oxazole- 4,5,6-triol can also be prepared by fermentation using newly isolated strains Micromonospora sp. SANK 62390, FERM BP-3521 and Amycolatopsis sp. SANK 60791, FERM BP-3513.
Bibliography:Application Number: DK19920301258T