ENZYMSTABILISIERUNG DURCH KATIONISCHE, OBERFLÄCHENAKTIVE SUBSTANZEN

The present invention provides methods and compositions for protein stabilization, particularly the stabilization of polymerases in aqueous solutions with cationic surfactants. The present invention further provides cationic surfactants, including polyethoxylated amines, that stabilize thermostable...

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Bibliographic Details
Main Authors HUANG, FEN, SHULTZ, JOHN W
Format Patent
LanguageGerman
Published 07.02.2008
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Summary:The present invention provides methods and compositions for protein stabilization, particularly the stabilization of polymerases in aqueous solutions with cationic surfactants. The present invention further provides cationic surfactants, including polyethoxylated amines, that stabilize thermostable and thermolabile enzymes in solution. These surfactants stabilize the activity of various enzymes, including thermostable DNA polymerases, thermolabile DNA polymerases and reverse transcriptases.
Bibliography:Application Number: DE19996036201T