N-AMIDINO- DERMORPHIN-DERIVAT

A peptide derivative having analgesic activity represented by the following formula: wherein Q represents D-Arg or L-Arg; and X represents for example NR -CHR R . Typical compounds include H2NC(NH)-Tyr-D-Arg-Phe-NHCH2CH2COOH and H2NC(NH)-Tyr-D-Arg-Phe-NHCH2CH2CONH2.

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Bibliographic Details
Main Authors NAKANO, MASAHARU FUJI ICAL INDUSTRIES, HONGO, KAZUYA FUJI ICAL INDUSTRIES, TAKE, NOBUHIRO FUJI ICAL INDUSTRIES, SAKURADA, SHINOBU, TAKESHIMA, SATOKO FUJI ICAL INDUSTRIES, MURAYAMA, KIMIE
Format Patent
LanguageGerman
Published 05.01.2000
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A peptide derivative having analgesic activity represented by the following formula: wherein Q represents D-Arg or L-Arg; and X represents for example NR -CHR R . Typical compounds include H2NC(NH)-Tyr-D-Arg-Phe-NHCH2CH2COOH and H2NC(NH)-Tyr-D-Arg-Phe-NHCH2CH2CONH2.
Bibliography:Application Number: DE19956011259T