1H-Indol-3-Acetamid-Derivate als sPLA2-Inhibitoren

A class of 1H-indole-3-acetamides, represented by the formula (I), and pharmaceutically acceptable salts thereof; is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

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Bibliographic Details
Main Authors DILLARD, ROBERT DELANE, BACH, NICHOLAS JAMES, DRAHEIM, SUSAN ELIZABETH, SCHEVITZ, RICHARD WALTER, HERMANN, ROBERT BELL
Format Patent
LanguageGerman
Published 23.12.1999
Edition6
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A class of 1H-indole-3-acetamides, represented by the formula (I), and pharmaceutically acceptable salts thereof; is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
Bibliography:Application Number: DE19946020068T