METHODEN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON BÖSARTIGEN ENTARTUNGEN, DIE IN ZUSAMMENHANG MIT EINER PROTEINKINASE STEHEN

Methods and compositions are disclosed for the treatment of malignancies in which a protein tyrosine kinase is associated. The malignancies may be treated with a gene transfer vehicle capable of infecting malignant cells, wherein the gene transfer vehicle carries a DNA construct comprising a DNA seq...

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Main Authors COOL, DEBORAH, E., SEATTLE, WA 98199, US, FISCHER, EDMOND, H., SEATTLE, WA 98105, US, KREBS, EDWIN, G., SEATTLE, WA 98112, US, TONKS, NICHOLAS, K., NEW YORK 11724, US
Format Patent
LanguageGerman
Published 05.10.1995
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Methods and compositions are disclosed for the treatment of malignancies in which a protein tyrosine kinase is associated. The malignancies may be treated with a gene transfer vehicle capable of infecting malignant cells, wherein the gene transfer vehicle carries a DNA construct comprising a DNA sequence encoding a protein tyrosine phosphatase (PTPase). Suitable DNA sequences include those encoding wild type, or carboxyl terminus truncated, PTPases.
Bibliography:Application Number: DE19916010034T