Cephalosporinverbindungen und Verfahren zu ihrer Herstellung

• Main Authors: YIM, HYEON JOO, DONG-KU, DAEJEON-SI, KR, LIM, JONG CHAN, YOUSEONG-KU, DAEJEON-SI, KR, OH, HUN SEUNG, YOUSEONG-KU, DAEJEON-SI, KR, BANG, CHAN SIK, YOUSEONG-KU, DAEJEON-SI, KR, KIM, YONG ZU, YOUSEONG-KU, DAEJEON-SI, KR, YEO, JAE HONG, YOUSEONG-KU, DAEJEON-SI, KR, KIM, WON SUP, YOUSEONG-KU, DAEJEON-SI, KR
• Format: Patent
• Language: German
• Published: 13.02.1997
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to new cephalosporin compounds of the formula (I), pharmaceutically acceptable non-toxic salts thereof, and physiologically hydrolyzable esters and solvates thereof, which have potent and broad antibacterial activities wherein R is a C1 SIMILAR 4 alkyl, C3 SIMILAR 4 alkenyl, C3 SIMILAR 4 alkynyl group or -C(R)(R)CO2H, wherein R and R are the same or different, and each is a hydrogen atom or a C1 SIMILAR 4 alkyl group, or R and R form a C3 SIMILAR 7 cycloalkyl group with the carbon atom to which they are linked; R is a C1 SIMILAR 4 alkyl, C3 SIMILAR 4 alkenyl or C3 SIMILAR 4 cycloalkyl group, a substituted or unsubstituted amino group, or a substituted or unsubstituted phenyl group; R is hydrogen or a C1 SIMILAR 4 alkyl group, and Q is N or CH; The invention further relates to a process for preparing said compounds, and to pharmaceutical compositions containing said compounds.